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B Cell Immunity Lab
Understanding how tissue environments shape B cell immunity
About
We are the B Cell Immunity Lab, based at the Blizard Institute, Queen Mary University of London.
Our research focuses on understanding how B cells develop, differentiate, and generate antibody responses in human tissues. We combine single-cell genomics, antibody repertoire sequencing, and functional immunology to investigate how B cell responses are shaped in infection, allergy, and autoimmunity
B cell differentiation
Mechanisms regulating germinal centre responses and plasma cell formation
Antibody repertoires
Clonal evolution and class switching analysed using single-cell and bulk sequencing
Tissue immunity
B cell responses in airway inflammation, infection, and autoimmunity
Our work integrates single-cell transcriptomics, BCR sequencing, and functional immunology in human tissues.
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